Annual report pursuant to Section 13 and 15(d)

Note 9 - Related Party Receivable (Details Textual)

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Note 9 - Related Party Receivable (Details Textual) - Chief Scientific Officer [Member] - Repayment Agreement of Improperly Expense Reimbursement [Member] - USD ($)
12 Months Ended
Aug. 10, 2016
Dec. 31, 2018
Due from Related Parties, Term 6 years  
Due from Related Parties, Total $ 658,000 $ 458,000
Due from Related Party, Discount $ 199,000  
Due from Related Party, Annual Installments   $ 100,000