Quarterly report pursuant to Section 13 or 15(d)

Note 4 - Stockholders' Equity - Share-based Compensation Expense (Details)

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Note 4 - Stockholders' Equity - Share-based Compensation Expense (Details) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Research and development expenses $ 134,695 $ 329,755 $ 570,273 $ 1,504,143
Research and Development Expense [Member]        
Research and development expenses 22,917 185,492 110,417 993,927
General and Administrative Expense [Member]        
Research and development expenses $ 111,778 $ 144,263 $ 459,856 $ 510,216