Quarterly report pursuant to Section 13 or 15(d)

Note 4 - Stockholders' Equity - Summary of Stock Option Activity (Details)

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Note 4 - Stockholders' Equity - Summary of Stock Option Activity (Details) - $ / shares
9 Months Ended 12 Months Ended
Sep. 30, 2019
Dec. 31, 2018
Options Outstanding (in shares) 81,674  
Options Outstanding, Weighted Average Exercise Price (in dollars per share) $ 215.60  
Weighted- average remaining contractual life (Year) 7 years 328 days 5 years 36 days
Options Granted (in shares) 228,183  
Options Granted, Weighted Average Exercise Price (in dollars per share) $ 7.78  
Options Exercised (in shares)  
Options Exercised, Weighted Average Exercise Price (in dollars per share)  
Options Forfeited/Expired (in shares) (10,127)  
Options Forfeited/Expired, Weighted Average Exercise Price (in dollars per share) $ 86.07  
Options Outstanding (in shares) 299,730 81,674
Options Outstanding, Weighted Average Exercise Price (in dollars per share) $ 61.78 $ 215.60
Options Exercisable (in shares) 206,347  
Options Exercisable, Weighted Average Exercise Price (in dollars per share) $ 86.15  
Options Exercisable, Weighted Average Remaining Contractual Life (Year) 7 years 73 days