Quarterly report pursuant to Section 13 or 15(d)

Note 4 - Stockholders' Equity (Tables)

v3.19.3
Note 4 - Stockholders' Equity (Tables)
9 Months Ended
Sep. 30, 2019
Notes Tables  
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
    Three Months Ended September 30,
    2019   2018
         
Research and development expenses   $
-
    $
22,917
 
General and administrative expenses    
294,600
     
111,778
 
Total   $
294,600
    $
134,695
 
    Nine Months Ended September 30,
    2019   2018
         
Research and development expenses   $
200,337
    $
110,417
 
General and administrative expenses    
561,007
     
459,856
 
Total   $
761,344
    $
570,273
 
Share-based Payment Arrangement, Option, Activity [Table Text Block]
    Number of Options  
Weighted-Average
Exercise Price
  Weighted-Average Remaining Contractual Life (in years)   Aggregate Intrinsic Value
                 
Outstanding at January 1, 2019    
81,674
    $
215.60
     
5.1
    $
-
 
Granted    
228,183
    $
7.78
     
 
     
 
 
Exercised    
-
    $
-
     
 
    $
-
 
Forfeited    
(10,127
)   $
86.07
     
 
     
 
 
Outstanding at September 30, 2019    
299,730
    $
61.78
     
7.9
    $
-
 
                                 
Exercisable at September 30, 2019    
206,347
    $
86.15
     
7.2
    $
-
 
Share-based Payment Arrangement, Option, Exercise Price Range [Table Text Block]
Range of Exercise Prices   Number of Options Outstanding  
Weighted-Average
Exercise Price
  Weighted-Average Remaining Contractual Life (in years)   Aggregate Intrinsic Value
$5.90
-
$6.00
   
58,010
    $
5.99
     
9.3
    $
-
 
$7.20
-
$8.80
   
162,593
    $
8.51
     
9.2
     
-
 
$22.20
-
$99.20
   
36,138
    $
33.20
     
5.6
     
-
 
$107.40
-
$1,102.41
   
42,989
    $
362.61
     
2.9
     
-
 
 
   
299,730
    $
61.78
     
7.9
    $
-
 
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
      Nine Months Ended September 30,  
      2019       2018  
                 
Annual dividend    
 
-
 
     
 
-
 
 
Expected life (in years)    
4.8
-
5.5 
     
2.5
-
5.3 
 
Risk free interest rate    
1.8%
-
2.5% 
     
2.7%
-
2.8% 
 
Expected volatility    
97%
-
115% 
     
97%
-
117% 
 
Schedule of Share-based Compensation, Warrant Activity [Table Text Block]
Range of Exercise Prices   Number of Warrants Outstanding   Range of Expiration Dates
 
$0.0001
 
   
1,048,166
   
perpetual
$2.19
-
$2.70
   
6,538,035
   
December 2020
-
August 2024
$3.38
-
$17.50
   
406,223
   
October 2023
-
July 2024
$22.20
-
$782.60
   
26,479
   
October 2019
-
July 2023
 
   
8,018,903