Quarterly report pursuant to Section 13 or 15(d)

Note 4 - Stockholders' Equity (Tables)

v3.19.2
Note 4 - Stockholders' Equity (Tables)
6 Months Ended
Jun. 30, 2019
Notes Tables  
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
    Three Months Ended June 30,
    2019   2018
         
Research and development expenses   $
-
    $
22,917
 
General and administrative expenses    
128,778
     
173,825
 
Total   $
128,778
    $
196,742
 
    Six Months Ended June 30,
    2019   2018
         
Research and development expenses   $
200,337
    $
87,500
 
General and administrative expenses    
266,407
     
348,077
 
Total   $
466,744
    $
435,577
 
Share-based Payment Arrangement, Option, Activity [Table Text Block]
    Number of Options   Weighted-Average Exercise Price   Weighted-Average Remaining Contractual Life (in years)   Aggregate Intrinsic Value
                 
Outstanding at January 1, 2019    
81,633
    $
215.60
     
5.1
    $
-
 
Granted    
46,379
    $
8.53
   
-
     
 
 
Exercised    
-
    $
-
   
 
    $
-
 
Forfeited    
(2,531
)   $
323.42
     
 
     
 
 
Outstanding at June 30, 2019    
125,481
    $
136.85
     
6.5
    $
-
 
                                 
Exercisable at June 30, 2019    
98,621
    $
171.27
     
5.7
    $
-
 
Share-based Payment Arrangement, Option, Exercise Price Range [Table Text Block]
Range of Exercise Prices   Number of Options Outstanding   Weighted-Average Exercise Price   Weighted-Average Remaining Contractual Life (in years)   Aggregate Intrinsic Value
$6.80
-
$10.00
   
46,379
    $
8.20
     
9.5
    $
-
 
$20.00
-
$70.00
   
29,432
    $
23.00
     
6.8
     
-
 
$70.20
-
$260.00
   
26,612
    $
195.20
     
3.8
     
-
 
$260.20
-
$520.00
   
14,937
    $
299.00
     
3.0
     
-
 
$520.20
-
$1,120.00
   
8,121
    $
793.00
     
3.4
     
-
 
 
   
125,481
    $
136.85
     
6.5
    $
-
 
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
    Six Months Ended June 30, 2019
     
Annual dividend  
 
-
 
Expected life (in years)  
5.0
-
5.5
Risk free interest rate  
1.9%
-
2.5%
Expected volatility  
97%
-
101%
Schedule of Share-based Compensation, Warrant Activity [Table Text Block]
Range of Exercise Prices   Number of Warrants Outstanding   Range of Expiration Dates
$6
-
$18
   
333,136
   
May 2021
-
August 2024
$22
-
$116
   
1,731
   
May 2021
-
May 2023
 
 $257 
 
   
1,965
   
 
January 2022
 
 
 $325 
 
   
8,727
   
 
March 2020
 
$442
-
$557
   
2,212
   
December 2019
-
January 2021
$691
-
$783
   
11,827
   
October 2019
-
October 2021
 
$1,043
 
   
577
   
 
July 2019
 
 
   
360,175