Quarterly report pursuant to Section 13 or 15(d)

Note 5 - Stockholders' Equity - Share-based Compensation Expense (Details)

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Note 5 - Stockholders' Equity - Share-based Compensation Expense (Details) - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Allocated Share-based Compensation Expense $ 651,949 $ 817,067 $ 1,174,388 $ 2,287,953
Research and Development Expense [Member]        
Allocated Share-based Compensation Expense 435,969 264,137 808,435 973,553
General and Administrative Expense [Member]        
Allocated Share-based Compensation Expense $ 215,980 $ 552,930 $ 365,953 $ 1,314,400